Could a probiotic help long COVID Patients' blood vessels?
NCT ID NCT05227170
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a probiotic called Lactobacillus plantarum 299v (Lp299v) can improve blood vessel function in people with Long COVID (PASC). The trial includes 80 adults who had COVID-19 30-180 days ago and have ongoing symptoms. Participants take either the probiotic or a placebo capsule for a period, and researchers measure changes in blood vessel health and inflammation markers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lactobacillus plantarum 299v (a probiotic)
What this could lead to
If it works, this could point toward a simple probiotic supplement to help improve blood vessel health and reduce inflammation in people with Long COVID.
What could go wrong
This is a small, early-stage trial with no phase designation, so results may not be conclusive. The probiotic is already in food products, but its effect on Long COVID symptoms is unproven.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States