Good bacteria floss could fight gum disease

NCT ID NCT07149493

Completed Disease control Sponsor: St. Anne's University Hospital Brno, Czech Republic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested a special dental floss coated with a probiotic (good bacteria) to see if it could reduce harmful mouth germs and improve gum health. Thirty-three healthy men used the probiotic floss and a placebo floss for two weeks each, with a break in between. Researchers measured plaque, gum bleeding, and levels of harmful bacteria.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ligilactobacillus salivarius (probiotic) infused into nanofiber dental floss
What this could lead to: If it works, this could point toward a simple way to improve gum health and reduce harmful bacteria using everyday dental floss.
What could go wrong: This is a small, early-stage trial with only 33 healthy men, so results may not apply to everyone. The effect on actual gum disease is still unclear.

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Conditions

The condition(s) this trial relates to.

dental caries gingivitis periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DENTAL HYGIENE GINGIVITIS AND PERIODONTAL DISEASES ORAL MICROBIOME PERIODONTAL HEALTH PREVENTION OF DENTAL CARIES PROBIOTICS, PERIODONTITIS

Good bacteria floss could fight gum disease

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

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