Major trial tests best way to boost radiation for prostate cancer

NCT ID NCT07426055

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing whether adding a focused radiation boost after standard short-course radiotherapy improves outcomes for men with localized prostate cancer. About 1,200 men will be randomly assigned to receive either standard SBRT alone or SBRT plus one of three boost methods: HDR brachytherapy, LDR brachytherapy, or an extra SBRT dose. The goal is to find which approach best prevents cancer recurrence while limiting side effects on urinary, bowel, and sexual function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Radiation therapy (SBRT, HDR brachytherapy, LDR brachytherapy, and external beam radiotherapy)

What this could lead to

If successful, this trial could show which radiation approach best controls prostate cancer while minimizing side effects, helping doctors choose the optimal treatment for future patients.

What could go wrong

This is a large, late-phase trial, but all treatments are already standard—so the benefit may be modest. Long follow-up is needed, and results may not apply to all prostate cancer types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adenocarcinoma prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affidea Nu-Med, Center of Oncological Diagnostics and Therapy

    RECRUITING

    Zamość, Lublin Voivodeship, 22-400, Poland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact