New combo treatment may sharpen vision in keratoconus patients
NCT ID NCT07372911
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining a laser vision correction (PRK) with corneal cross-linking improves eyesight and corneal shape better than cross-linking alone in people with keratoconus, a condition that thins and bulges the cornea. Fifty adults aged 18-40 with mild to moderate keratoconus will be randomly assigned to one of two groups. The main goal is to see if the combination leads to better corrected vision after one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Excimer laser (PRK) and riboflavin-UVA cross-linking
- What this could lead to
- If successful, this approach could offer better vision correction and corneal stability for people with keratoconus, potentially reducing the need for glasses or contact lenses.
- What could go wrong
- This is a small, early-stage trial with only 50 participants, so results may not apply to everyone. Risks include corneal haze, infection, or no significant improvement over standard treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Instituto de Oftalmología FAP Conde de Valenciana, IAP Sede Centro
RECRUITINGMexico City, Mexico City, 06800, Mexico
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Promising new eye treatment could halt vision loss from keratoconus