Brain training device aims to restore joy in depression
NCT ID NCT06982820
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new treatment called Prism for people with major depression who have lost interest or pleasure in activities (anhedonia). Prism is a software device that uses neurofeedback to train the brain's reward system. About 170 participants will receive either real Prism therapy or a sham version to see if it improves mood and pleasure. The study uses MRI and EEG to measure brain activity.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Butler Hospital
RECRUITINGProvidence, Rhode Island, 02906, United States
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Houston Center For Advanced Psychiatric Treatment
RECRUITINGHouston, Texas, 77401, United States
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Sheba Medical Center
RECRUITINGRamat Gan, Israel
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