Brain-Training device aims to restore joy in depressed patients
NCT ID NCT06982820
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times
Summary
This study tests a new treatment called Prism for people with major depression who have lost interest or pleasure in activities (anhedonia). Prism is a software device that uses neurofeedback to train the brain's reward system. About 170 adults will be randomly assigned to receive either real Prism therapy or a sham (fake) version to see if the real treatment works better. Participants will also have MRI and EEG scans to measure brain activity.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Butler Hospital
RECRUITINGProvidence, Rhode Island, 02906, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Houston Center For Advanced Psychiatric Treatment
RECRUITINGHouston, Texas, 77401, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sheba Medical Center
RECRUITINGRamat Gan, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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