Tiny trial hopes to zap migraines away with implanted nerve device

NCT ID NCT05858801

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests a new device called PRIMUS that stimulates nerves in the head and face to treat chronic migraine. Only 7 people with hard-to-treat migraines are taking part. The main goal is to see if the device is safe, not yet if it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PRIMUS system (a craniofacial peripheral nerve stimulation device)

What this could lead to

If it works, this could point toward a new drug-free option for people with chronic migraine who haven't found relief from other treatments.

What could go wrong

This is a very early, tiny study (7 people) focused only on safety, not effectiveness. The device may not reduce migraines, and risks like infection or nerve damage are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AZ Delta

    Roeselare, Belgium