Tiny trial hopes to zap migraines away with implanted nerve device

NCT ID NCT05858801

Ongoing Symptom relief Sponsor: Salvia BioElectronics Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 10, 2026 · Updated 3 times

Summary

This early study tests a new device called PRIMUS that stimulates nerves in the head and face to treat chronic migraine. Only 7 people with hard-to-treat migraines are taking part. The main goal is to see if the device is safe, not yet if it works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: PRIMUS system (a craniofacial peripheral nerve stimulation device)
What this could lead to: If it works, this could point toward a new drug-free option for people with chronic migraine who haven't found relief from other treatments.
What could go wrong: This is a very early, tiny study (7 people) focused only on safety, not effectiveness. The device may not reduce migraines, and risks like infection or nerve damage are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC MIGRAINE

Contacts and locations

Locations

AZ Delta

Roeselare, Belgium

More trials for these conditions

Other studies related to the condition(s) this trial covers.