Vacuum therapy may stop deadly leaks after esophageal cancer surgery

NCT ID NCT06097078

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a special vacuum device placed inside the esophagus right after cancer surgery to prevent dangerous leaks where the stomach is reconnected to the esophagus. About 44 adults having minimally invasive esophageal cancer surgery will receive this preventive treatment. The goal is to see if it lowers the rate of anastomotic leaks, a serious complication that can lead to infection or death.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Eso-SPONGE® device (endoluminal vacuum therapy)

What this could lead to

If it works, this could offer a way to prevent a serious complication after esophageal cancer surgery, potentially reducing infections and deaths.

What could go wrong

This is a small, early-stage study with only 44 participants and no comparison group, so results may not apply broadly. The device itself carries risks like discomfort or rare injury.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Anastomotic Leak esophageal cancer Esophageal Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Clinic de Barcelona

    Barcelona, Catalonia, 08036, Spain