Kidney shield: new trial tests cilastatin to prevent Drug-Induced injury

NCT ID NCT06886464

First seen Jan 07, 2026 · Last updated May 16, 2026 · Updated 22 times

Summary

This study tests whether the drug cilastatin can prevent acute kidney injury in hospitalized patients who must take medications known to harm the kidneys. About 700 adults receiving certain antibiotics, chemotherapy, or contrast dyes will receive either cilastatin or a placebo every 6 hours. Researchers will monitor kidney function daily and follow up at 90 days to see if cilastatin reduces injury.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE KIDNEY INJURY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Alberta

    RECRUITING

    Edmonton, Alberta, T6G 2R3, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Calgary

    RECRUITING

    Calgary, Alberta, T2N 1N4, Canada

Conditions

Explore the condition pages connected to this study.