New balloon treatment may shorten blood thinner use for heart patients

NCT ID NCT06321757

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a paclitaxel-coated balloon to open small coronary arteries in people with heart disease who also have a high risk of bleeding. About 501 participants will receive the balloon treatment and then take blood thinners for either the standard duration or just 7 days. The goal is to see if the balloon works well and if a shorter course of blood thinners is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

paclitaxel-coated balloon

What this could lead to

If successful, this could show that a drug-coated balloon with just 7 days of blood thinners is safe and effective for people with small heart arteries and high bleeding risk.

What could go wrong

This is an observational study, not a randomized trial, so results may be less definitive. The short blood thinner regimen might still carry bleeding or clotting risks.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder coronary stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Azienda Ospedaliera Ospedali Riuniti Villa Sofia - Cervello

    RECRUITING

    Palermo, 90146, Italy

  • Clinica Mediterranea

    RECRUITING

    Naples, 08122, Italy

  • Hospital Clinico Universitario de Valladolid

    RECRUITING

    Valladolid, 47003, Spain

  • Hospital General Universitario Dr. Balmis

    RECRUITING

    Alicante, 03010, Spain

  • Hospital General Universitario de Albacete

    RECRUITING

    Albacete, 02008, Spain

  • Hospital General Universitario de Ciudad Real

    RECRUITING

    Ciudad Real, 13005, Spain

  • Hospital Universitari de Bellvitge

    RECRUITING

    L'Hospitalet de Llobregat, 08907, Spain

  • Hospital Universitario Clinico San Cecilio

    RECRUITING

    Granada, 18016, Spain

  • Hospital Universitario Juan Ramon Jimenez

    RECRUITING

    Huelva, 21005, Spain

  • Hospital Universitario Virgen del Rocío

    RECRUITING

    Seville, 41013, Spain

  • Hospital Universitario Y Politecnico La Fe

    RECRUITING

    Valencia, 46026, Spain

  • Hospital Universitario de Canarias

    RECRUITING

    San Cristóbal de La Laguna, Spain

  • Hospital Universitario de Cruces

    RECRUITING

    Barakaldo, 49803, Spain

  • Hospital Universitario de Gran Canaria Doctor Negrín

    RECRUITING

    Las Palmas de Gran Canaria, 35010, Spain

  • Hospital Universitario de La Princesa

    RECRUITING

    Madrid, 28006, Spain

  • Hospital Universitario de Leon

    RECRUITING

    León, 24071, Spain

  • ULS Santa Maria

    RECRUITING

    Lisbon, Portugal

  • Ulslo-H.Santa Cruz

    RECRUITING

    Carnaxide, Portugal

  • University Hospital HM Montepríncipe

    RECRUITING

    Boadilla del Monte, 28660, Spain