Kidney function may change how TB drug works

NCT ID NCT03896750

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 29 times

Summary

This study looked at how the tuberculosis drug pretomanid is handled by the body in people with different levels of kidney function. Researchers gave a single dose to 12 adults with normal or impaired kidneys and measured drug levels and safety. The goal was to see if kidney problems affect drug exposure, which could help doctors adjust doses in the future.

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Contacts and locations

Locations

  • Advanced Pharma - Miami

    Miami, Florida, 33147, United States

  • Alliance for Multispecialty Research, LLC - Knoxville

    Knoxville, Tennessee, 37920, United States

  • Saint Louis University Center for Vaccine Development

    St Louis, Missouri, 63104-1015, United States

Conditions

Explore the condition pages connected to this study.