Could a 12-Week TB drug combo replace 6-Month standard care?
NCT ID NCT05556746
First seen Feb 13, 2026 · Last updated May 13, 2026 · Updated 14 times
Summary
This study tests whether a 12-week combination of four drugs (bedaquiline, clofazimine, pyrazinamide, and delamanid) works better than the standard 6-month treatment for drug-susceptible tuberculosis. About 94 adults with active TB in the lungs will be randomly assigned to either the short course or standard therapy. The main goal is to see how quickly the bacteria are cleared from sputum, and to check for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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GHESKIO
Port-au-Prince, Haiti
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University of Cape Town
Cape Town, South Africa
Conditions
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