Can diet and exercise in pregnancy shape a Child's health for years?

NCT ID NCT05503849

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers in Guangzhou are testing whether a structured program of healthy eating, physical activity, and lifestyle habits during pregnancy improves outcomes for both mothers and their babies. The study enrolls pregnant women before 20 weeks who plan to deliver at Guangzhou Women and Children's Medical Center and stay in the area for at least three years. The program includes balanced meals based on Chinese dietary guidelines, regular exercise, and changes to sleep and sun exposure. Researchers track maternal weight gain, newborn size, and the health of both mother and child over three years, including blood sugar, cholesterol, and growth measures.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a lifestyle program combining diet, physical activity, and habits like sleep and sun exposure
What this could lead to
If it works, this could give pregnant women a clear, practical way to lower their risk of complications like gestational diabetes and support healthier growth for their children.
What could go wrong
Changing diet and activity during pregnancy is hard to sustain, and the trial may not show clear benefits. The results will apply mainly to women in Guangzhou who join early in pregnancy.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,160 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2024

Expected to finish

Sep 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pregnant women attending prenatal care at Guangzhou Women and Children's Medical Center (GWCMC) \<20 weeks' gestation * Pregnant women plan to deliver at GWCMC * Pregnant women intend to reside in Guangzhou for at least 3 years Exclusion Criteria: * Multiple pregnancies * Existing medical conditions (uncontrolled diabetes, hypertension or thyroid disease; other serious cardiovascular diseases, respiratory or systematic disorders) * Use of drugs (aspirin, metformin, low molecular weight heparin) * Women with reading and/or writing difficulties * Women with serious mental disorders * Women with eating disorders

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Fuying Campus, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China

    RECRUITING

    Guangzhou, China

  • Zhujiang new town campus, Guangzhou Women and Children&#39;s Medical Center, China

    RECRUITING

    Guangzhou, China

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