Which painkiller wins for Post-Mastectomy pain?

NCT ID NCT07567924

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This completed trial tested whether pregabalin (a nerve pain drug) works better than acetaminophen (a common pain reliever) for post-mastectomy pain syndrome. 158 women took one of the two medications for 14 days, and their pain levels were measured at 2 and 6 weeks. The goal is to find a more effective way to manage this chronic pain after breast cancer surgery.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
pregabalin and acetaminophen
What this could lead to
If pregabalin proves better, it could offer a more effective pain relief option for women suffering from post-mastectomy pain syndrome.
What could go wrong
This is a small, single-blinded trial with short-term treatment (14 days). Results may not apply to all patients, and both drugs have side effects like dizziness or allergic reactions.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sindh Institute of urology and Transplantation

    Karachi, Pakistan

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