New surgical trick may stop chronic pain after breast cancer surgery
NCT ID NCT06580951
First seen Jun 25, 2026 · Last updated Jul 08, 2026 · Updated 3 times
Summary
This study tests a procedure called regenerative peripheral nerve interface (RPNI) done during mastectomy with immediate reconstruction. The goal is to prevent chronic nerve pain that often follows breast cancer surgery. About 200 women will be randomly assigned to get either standard surgery or surgery plus RPNI, and their pain and quality of life will be tracked for a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Regenerative peripheral nerve interface (RPNI) procedure
- What this could lead to
- If it works, this could offer a way to prevent chronic nerve pain after mastectomy, improving quality of life for many breast cancer survivors.
- What could go wrong
- This is an early-stage, single-center trial with 200 participants. The procedure may not reduce pain significantly, and there are surgical risks like infection or bleeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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