New surgical trick may stop chronic pain after breast cancer surgery
NCT ID NCT06580951
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a procedure called regenerative peripheral nerve interface (RPNI) done during mastectomy with immediate reconstruction. The goal is to prevent chronic nerve pain that often follows breast cancer surgery. About 200 women will be randomly assigned to get either standard surgery or surgery plus RPNI, and their pain and quality of life will be tracked for a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Regenerative peripheral nerve interface (RPNI) procedure
What this could lead to
If it works, this could offer a way to prevent chronic nerve pain after mastectomy, improving quality of life for many breast cancer survivors.
What could go wrong
This is an early-stage, single-center trial with 200 participants. The procedure may not reduce pain significantly, and there are surgical risks like infection or bleeding.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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