Simple blood test may replace colonoscopy for colitis patients
NCT ID NCT06372613
First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 4 times
Summary
This study is testing whether a blood test measuring a protein called LRG can tell if the gut lining has healed in people with ulcerative colitis. Researchers will compare blood LRG levels with colonoscopy and tissue samples in 100 patients. If the blood test works, it could offer a less invasive way to monitor the disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple blood test to check if ulcerative colitis is in remission, potentially reducing the need for invasive colonoscopies.
- What could go wrong
- This is an early observational study with only 100 participants, so the results may not apply to all patients. The LRG test may not be accurate enough to replace colonoscopy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ULCERATIVE COLITIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Showa Inan General Hospital
RECRUITINGKomagane, Japan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Sound waves vs. scope: a gentler way to spot pouch inflammation?
- Can we predict how kids with IBD will respond to treatment?
- Can switching IBD meds heal the gut when symptoms are quiet?
- Can a milk sugar tame IBD symptoms?
- Could an extra flu shot shield vulnerable kids?
- Can a glass of pomegranate juice tame gut inflammation?