Personalized heart care: biomarker score may cut heart risks

NCT ID NCT04755413

Ongoing Disease control Sponsor: Emory University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using a blood test score (based on four proteins linked to heart risk) can help doctors choose the best treatments for people with coronary artery disease. 276 adults with stable heart disease will either get standard care or a customized plan that includes lifestyle advice and medications like statins. The goal is to see if the personalized approach lowers these biomarker levels and reduces complications like heart attacks or hospitalizations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Lifestyle advice, statins, ezetimibe, and other medications tailored to biomarker levels
What this could lead to: If successful, this approach could help doctors personalize heart disease treatment to reduce the risk of heart attacks and other complications.
What could go wrong: This is a relatively small, early-stage study focused on biomarker changes, not yet proven to prevent major heart events. The results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE

Contacts and locations

Locations

Emory Johns Creek Hospiatl

Atlanta, Georgia, 30097, United States
Emory Saint Joseph's Hospital

Atlanta, Georgia, 30342, United States
Emory University Hospital

Atlanta, Georgia, 30322, United States
Emory University Hospital Midtown

Atlanta, Georgia, 30308, United States
The Emory Clinic

Atlanta, Georgia, 30324, United States

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