Stroke trial aims to prevent second attacks with tailored blood thinners

NCT ID NCT06853535

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether using a blood test to guide antiplatelet therapy can better prevent recurrent strokes in people who have had a mild stroke or transient ischemic attack (TIA). About 5,100 participants will be assigned to either standard clopidogrel or ticagrelor based on their platelet function. The goal is to see if ticagrelor reduces the risk of another stroke within 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ticagrelor and clopidogrel (antiplatelet drugs)

What this could lead to

If successful, this could provide a more effective antiplatelet strategy for stroke patients who don't respond well to clopidogrel, reducing their risk of another stroke.

What could go wrong

This is a large Phase 3 trial, but it only includes patients with mild strokes or TIAs, so results may not apply to all stroke patients. There is also a risk of bleeding with antiplatelet therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE ISCHEMIC STROKE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

ischemic stroke transient ischemic attack

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sichuan Provincial People's Hospital

    RECRUITING

    Chengdu, Sichuan, 610072, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••