One-Shot radiation before breast cancer surgery shows promise
NCT ID NCT02482376
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase II trial tests a single, high-dose radiation treatment given before surgery for early-stage breast cancer. The goal is to see if this approach leads to good or excellent cosmetic results and reduces the need for multiple radiation sessions. About 110 women with small, early breast cancers will receive one focused radiation dose, then undergo standard surgery. Researchers will track cosmetic outcomes and cancer control over three years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Stereotactic body radiotherapy (SBRT) - a single high-dose radiation beam
What this could lead to
If successful, this could offer a shorter, more convenient radiation option before surgery for early breast cancer, potentially with better cosmetic results and fewer side effects.
What could go wrong
This is a phase II trial with only 110 participants, so results may not apply to all patients. The single high-dose radiation could cause unexpected tissue damage or poor cosmetic outcomes in some cases.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Duke Cancer Center
Durham, North Carolina, 27710, United States