Immunotherapy combo before liver surgery shows promise for advanced colorectal cancer

NCT ID NCT03844750

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested two drugs, pembrolizumab and vactosertib, given before and after surgery to remove liver tumors in people with colorectal cancer that had spread to the liver. The goal was to see if these drugs could shrink the liver tumors before surgery and lower the chance of cancer coming back after surgery. The study was stopped early and included only 6 participants.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm liver cancer metastatic malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94143, United States