Can a blood test predict which cGVHD treatment works best?
NCT ID NCT04431479
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study enrolls 300 adults with chronic graft-versus-host disease (cGVHD) who are about to start a new therapy. Researchers will collect blood samples and medical data before and after treatment to look for changes that might predict how well a patient responds. The goal is to find markers that could guide treatment decisions in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors choose the most effective treatment for each patient with chronic graft-versus-host disease, improving outcomes and reducing trial-and-error.
What could go wrong
This is an observational study, not a treatment trial. It may not identify reliable predictors, and results may not change clinical practice for years.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Dana-Farber Harvard Cancer Center
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Fred Hutch/University of Washington Cancer Consortium
RECRUITINGSeattle, Washington, 98109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Roswell Park Cancer Institute
COMPLETEDBuffalo, New York, 14263, United States
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UPMC Hillman Cancer Center
COMPLETEDPittsburgh, Pennsylvania, 15232, United States
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University of Florida
COMPLETEDGainesville, Florida, 32610, United States
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University of Minnesota/Masonic Cancer Center
COMPLETEDMinneapolis, Minnesota, 55455, United States
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Vancouver General Hospital/BC Cancer
COMPLETEDVancouver, British Columbia, V5Z 4E6, Canada
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Vanderbilt University/Ingram Cancer Center
COMPLETEDNashville, Tennessee, 37232, United States