Can a vitamin-like pill ease tough schizophrenia symptoms?

NCT ID NCT07393464

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a supplement called pyrroloquinoline quinone (PQQ) can help reduce negative symptoms (like lack of motivation) and improve thinking skills in people with chronic schizophrenia. About 70 adults will receive either PQQ or a placebo for 8 weeks, and researchers will track changes using questionnaires and brain scans. The goal is to see if targeting cell energy and inflammation can offer a new way to manage these hard-to-treat symptoms.

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Conditions

The condition(s) this trial relates to.

Neurobehavioral Manifestations schizophrenia

As listed by the trial registrant

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