New hope for kidney patients: experimental drug takes on membranous nephropathy

NCT ID NCT07204275

Recruiting now Disease control Sponsor: Vertex Pharmaceuticals Incorporated Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 23 times

Summary

This study tests a new drug, povetacicept, against a standard treatment for primary membranous nephropathy, a kidney disease that can lead to kidney failure. About 176 adults will take part to see if the new drug can put the disease into remission more safely and effectively. The goal is to control the disease and reduce the need for harsh immune-suppressing drugs.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Academic Medical Research Institute (AMRI)
RECRUITING

Los Angeles, California, 90022, United States
Azienda Ospedaliera Universitaria Federico II
RECRUITING

Naples, Italy
Beaumont Hospital
RECRUITING

Dublin, Ireland
Beijing Tsinghua Changgung Hospital
RECRUITING

Beijing, China
Bioresearch Partner
RECRUITING

Miami, Florida, 33127, United States
CARE Institute-Boise Kidney
RECRUITING

Boise, Idaho, 83706, United States
CTR Oakwater, LLC
RECRUITING

Orlando, Florida, 32806, United States
Carolina Nephrology Greenville
RECRUITING

Greenville, South Carolina, 29605, United States
Carolina Nephrology, PA
RECRUITING

Spartanburg, South Carolina, 29306, United States
Charite - Universitaetsmedizin Berlin Campus Benjamin Frankl
RECRUITING

Allemagne, Germany
Clinica Universidad de Navarra - Nefrología
RECRUITING

Pamplona, Spain
Clinical Site Partners, LLC - Orlando
RECRUITING

Winter Park, Florida, 32789, United States
DaVita Clinical Research Columbus
RECRUITING

Columbus, Georgia, 31904, United States
DaVita Clinical Research Edina
RECRUITING

Edina, Minnesota, 55435, United States
DaVita Clinical Research Houston
RECRUITING

Houston, Texas, 77054, United States
Dalian Municipal Central Hospital
RECRUITING

Dalian, China
Davita Clinical Research San Antonio
RECRUITING

San Antonio, Texas, 78251, United States
Doncaster and Bassetlaw Hospitals NHS Foundation Trust - Doncaster Royal Infirmary
RECRUITING

Doncaster, United Kingdom
Dongguan People's Hospital
RECRUITING

Dongguan, China
El Paso Kidney Specialists
RECRUITING

El Paso, Texas, 79902, United States
Fondazione Salvatore Maugeri - Nefrologia e Dialisi
RECRUITING

Pavia, Italy
Freire Pesquisa Clinica
RECRUITING

Belo Horizonte, Brazil
Fujita Health University
RECRUITING

Toyoake-Shi, Japan
Fundação Bahiana de Infectologia
RECRUITING

Salvador, Brazil
Fuyang People's Hospital
RECRUITING

Fuyang, China
Georgia Nephrology
RECRUITING

Lawrenceville, Georgia, 30046, United States
Guangdong Provincial People's Hospital
RECRUITING

Guangzhou, China
Hallym University Sacred Heart Hospital
RECRUITING

Anyang-si, South Korea
Hospital Ribera Polusa
RECRUITING

Lugo, Spain
Hospital Universitari Vall D Hebron
RECRUITING

Barcelona, Spain
Hospital Universitario Reina Sofia
RECRUITING

Córdoba, Spain
Hospital Universitario Virgen de la Macarena - Nefrología
RECRUITING

Seville, Spain
Hospital das Clinicas da Faculdade de Medicina da USP - HC- FMUSP
RECRUITING

São Paulo, Brazil
IRCCS Ospedale Policlinico San Martino
RECRUITING

Genova, Italy
Kanazawa University Hospital
RECRUITING

Kanazawa, Japan
Kasugai Municipal Hospital
RECRUITING

Kasugai, Japan
Kidney Specialists of Southern Nevada
RECRUITING

Las Vegas, Nevada, 89107, United States
Klinikum St. Georg gGmbH - Nephrology
RECRUITING

Leipzig, Germany
Korea University Anam Hospital - Nephrology
RECRUITING

Seoul, South Korea
Kyung Hee University Hospital at Gangdong - Nephrology
RECRUITING

Seoul, South Korea
Liu Zhou Works Hospital
RECRUITING

Liuzhou, China
Milwaukee Neprologists, SC
RECRUITING

Wauwatosa, Wisconsin, 53226, United States
NANI Research
RECRUITING

Hinsdale, Illinois, 60521, United States
NHS Lothian - Royal Infirmary of Edinburgh
RECRUITING

Edinburgh, United Kingdom
Nagoya University Hospital
RECRUITING

Shōwaku, Japan
Nanyang Central Hospital
RECRUITING

Nanyang, China
Okayama University Hospital
RECRUITING

Okayama, Japan
Peking University First Hospital
RECRUITING

Beijing, China
Provecta Research Network
RECRUITING

Houston, Texas, 77027, United States
Renal Associates
RECRUITING

Montgomery, Alabama, 36117, United States
Renji Hospital Shanghai Jiaotong University School of Medicine
RECRUITING

Shanghai, China
Samsung Medical Center - Nephrology
RECRUITING

Seoul, South Korea
Santa Casa de Misericordia
RECRUITING

Porto Alegre, Brazil
Severance Hospital, Yonsei University Health System - Nephrology
RECRUITING

Seoul, South Korea
Shanghai General Hospital
RECRUITING

Shanghai, China
Sichuan Academy of Medical Sciences ＆ Sichuan Provincial People's Hospital
RECRUITING

Chengdu, China
Southwest Kidney Institute, PLC (SKI) - Surprise
RECRUITING

Surprise, Arizona, 85374, United States
St George Private Hospital
RECRUITING

Kogarah, Australia
St George's University Hospitals NHS Foundation Trust - St George's Hospital- Renal Medicine
RECRUITING

London, United Kingdom
Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont
RECRUITING

Szeged, Hungary
Tai'an City Central Hosptial
RECRUITING

Tai’an, China
The 2nd Affiliated Hospital of Harbin Medical University
RECRUITING

Harbin, China
The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University
RECRUITING

Huai'an, China
The First Affiliated Hospital of Baotou Medical College
RECRUITING

Baotou, China
The First Affiliated Hospital of Bengbu Medical University
RECRUITING

Bengbu, China
The First Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, China
The First Affiliated Hospital of Ningbo University
RECRUITING

Ningbo, China
The First Affiliated Hospital of Xi 'an Jiaotong University
RECRUITING

Xi'an, China
The First Affiliated Hospital of Xiamen University
RECRUITING

Xiamen, China
The First Affiliated Hospital,Sun Yat-sen University
RECRUITING

Guangzhou, China
The First Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, China
The Fourth Hospital of Hebei Medical Univesrsity
RECRUITING

Shijiazhuang, China
The People's Hospital of Guangxi Zhuang Autonomous Region
RECRUITING

Nanning, China
The Royal Wolverhampton NHS Trust - New Cross Hospital
RECRUITING

Wolverhampton, United Kingdom
The Second Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, China
The Second Norman Bethune Hospital of Jilin University
RECRUITING

Changchun, China
The Second Qilu Hospital of Shandong University
RECRUITING

Jinan, China
The University of Osaka Hospital
RECRUITING

Suita, Japan
Universitaetsklinikum Leipzig - Medizinische Klinik und Poliklinik III - Klinik und Poliklinik fuer Endokrinologie, Nephrologie
RECRUITING

Leipzig, Germany
Universitaetsklinikum Wuerzburg - Innere Medizin, Nephrologie
RECRUITING

Würzburg, Germany
University Hospital Galway
RECRUITING

Galway, Ireland
University Hospital of Derby and Burton NHS Foundation Trust - Royal Derby Hospital
RECRUITING

Derby, United Kingdom
University of Newcastle - John Hunter Hospital (JHH)
RECRUITING

New Lambton Heights, Australia
Utah Kidney Research
RECRUITING

Salt Lake City, Utah, 84115, United States
Valiance Clinical Research - Internal Medicine
RECRUITING

Tarzana, California, 91356, United States
Vseobecna fakultni nemocnice v Praze - Klinika nefrologie
RECRUITING

Prague, Czechia
Weifang People's Hospital
RECRUITING

Weifang, China
Western Nephrology & Metabolic Bone Disease PC
RECRUITING

Arvada, Colorado, 80002, United States
Wuxi People's Hospital
RECRUITING

Wuxi, China
Xiangya Hospital of Central South University
RECRUITING

Changsha, China
Yantai YuHuangDing Hospital
RECRUITING

Yantai, China
Yichang Central People Hospital
RECRUITING

Yichang, China
Yongin Severance Hospital - Nephrology
RECRUITING

Yongin-si, South Korea

Conditions

Explore the condition pages connected to this study.

PRIMARY MEMBRANOUS NEPHROPATHY