Weight-Loss drug shows promise against kidney stones in obesity study
NCT ID NCT04621929
First seen Feb 01, 2026 · Last updated May 14, 2026 · Updated 14 times
Summary
This study tested whether the weight-loss drug phentermine/topiramate could help control uric acid kidney stones in people with obesity and type 2 diabetes or pre-diabetes. 19 participants were randomly assigned to either the drug or standard care (citrate, allopurinol, diet) for 18 months. The main goal was to see if the drug reduced stone size, with secondary goals of weight loss, improved urine pH, and better blood sugar control.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Florida
Gainesville, Florida, 32610, United States
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