New study tracks best way to treat recurrent breast cancer with radiation and heat

NCT ID NCT06452485

Recruiting now Knowledge-focused Sponsor: Amsterdam UMC, location VUmc Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This study follows 500 breast cancer patients whose cancer has returned in the same area (locoregional recurrence). They receive standard care: re-irradiation with or without hyperthermia (heat therapy). The goal is to track side effects, quality of life, and survival over five years using patient questionnaires. The data will help design a future randomized trial to compare these treatments more directly.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could provide real-world data to help doctors and patients make better decisions about re-irradiation and hyperthermia for recurrent breast cancer.
What could go wrong: This is an observational study, not a treatment trial, so it will not directly test whether one approach is better. Results depend on patient reports and may not apply to all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Hyperthermia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER HYPERTHERMIA LOCOREGIONAL RECURRENCE RE-IRRADIATION

Contacts and locations

Locations

Amsterdam UMC
RECRUITING

Amsterdam, Netherlands

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