Gut health boost may tame immunotherapy side effects in head and neck cancer

NCT ID NCT07485296

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a postbiotic supplement (Postbiotix-HLA™) can reduce immune-related side effects in 45 people with recurrent or metastatic head and neck cancer who are receiving the immunotherapy drug pembrolizumab. Participants will take either the supplement or a placebo for 4 cycles. The goal is to see if the supplement changes gut and mouth bacteria and helps the immune system handle treatment better.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Recurrence Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Istituto Clinico Humanitas

    RECRUITING

    Rozzano, Milano, 20089, Italy

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