New hope for head and neck cancer: drug combo shows promise after standard treatment fails

NCT ID NCT06856213

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a chemotherapy drug (paclitaxel) to a targeted therapy (cetuximab) works better than cetuximab alone for people with advanced head and neck cancer that has worsened after initial treatment. About 65 adults with recurrent or metastatic squamous cell carcinoma of the head and neck will be randomly assigned to one of two treatment groups. The goal is to see how many patients' tumors shrink or disappear.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centro Oncológico de Galicia (La Coruña)

    RECRUITING

    A Coruña, La Coruña, 15009, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Complejo Hospitalario de Navarra (Pamplona)

    RECRUITING

    Pamplona, Navarre, 31008, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Complejo Hospitalario de Salamanca (Salamanca)

    RECRUITING

    Salamanca, Salamanca, 37007, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Clínico San Carlos

    RECRUITING

    Madrid, Madrid, 28040, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Clínico Universitario de Santiago de Compostela

    RECRUITING

    Santiago de Compostela, A Coruña, 15706, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Infanta Leonor (Madrid)

    RECRUITING

    Vallecas, Madrid, 28031, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Regional Universitario de Málaga

    RECRUITING

    Málaga, Málaga, 29010, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitario 12 de Octubre (Madrid)

    WITHDRAWN

    Madrid, Madrid, 28041, Spain

  • Hospital Universitario Lucus Augusti

    RECRUITING

    Lugo, Lugo, 27003, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitario Marqués de Valdecilla (Santander)

    RECRUITING

    Santander, Cantabria, 39008, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitario Virgen de Valme (Sevilla)

    RECRUITING

    Seville, Sevilla, 41014, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitario Virgen de las Nieves

    RECRUITING

    Granada, Granada, 18014, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitario Virgen del Rocío (Sevilla)

    RECRUITING

    Seville, Sevilla, 41013, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitario de Canarias (La laguna)

    RECRUITING

    San Cristóbal de La Laguna, Santa Cruz de Tenerife, 38320, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospital Universitario de Toledo

    RECRUITING

    Toledo, Toledo, 45007, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Instituto Catalán de Oncología - Badalona

    RECRUITING

    Badalona, Barcelona, 08916, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Instituto Catalán de Oncología - Hospital Duran i Reynals

    RECRUITING

    Barcelona, Barcelona, 08908, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact