Could a Pre-Chemo drug shield bone marrow in head and neck cancer?

NCT ID NCT07679997

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This trial tests whether giving trilaciclib before chemotherapy and immunotherapy can protect bone marrow in people with advanced head and neck cancer. The goal is to reduce dangerous drops in blood cell counts, allowing patients to receive their full chemo doses on schedule. About 32 adults with recurrent or metastatic head and neck squamous cell carcinoma will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

trilaciclib

What this could lead to

If it works, this could help people with advanced head and neck cancer complete chemotherapy on time with fewer side effects like low blood cell counts.

What could go wrong

This is a small, early-phase trial with only 32 participants, so results may not apply to everyone. The drug may not reduce side effects as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••