Radiation after surgery may keep tongue cancer at bay for High-Risk patients

NCT ID NCT07402525

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether giving radiation therapy after surgery can delay the return of early-stage tongue cancer in patients who have certain risk factors. About 190 adults aged 18 to 70 will be randomly assigned to either receive radiation or just be monitored. The goal is to see if radiation improves how long patients stay cancer-free and their overall survival, while also checking side effects and quality of life.

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Conditions

The condition(s) this trial relates to.

Squamous Cell Carcinoma of Head and Neck squamous cell carcinoma of the oral tongue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cancer Hospital Chinese Academy of Medical Sciences

    NOT_YET_RECRUITING

    Chaoyang, Beijing Municipality, 100020, China

  • Cancer prevention and treatment center, sun yat-sen university

    NOT_YET_RECRUITING

    Guandong, Guangdong, 510060, China

  • Fudan University Shanghai Cancer Center

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

  • Fujian Cancer Hospital

    NOT_YET_RECRUITING

    Fuzhou, Fujian, 350014, China

  • Harbin Medical University Cancer Hospital

    NOT_YET_RECRUITING

    Harbin, Heilongjiang, 150081, China

  • Hunan Provincial People's Hospital

    NOT_YET_RECRUITING

    Changsha, Hunan, 410005, China

  • Hunan cancer hospital

    NOT_YET_RECRUITING

    Changsha, Hunan, 410008, China

  • Huzhou Center Hospital

    NOT_YET_RECRUITING

    Huzhou, Zhejiang, 313000, China

  • Jiangxi Cancer Hospital

    NOT_YET_RECRUITING

    Nanchang, Jiangxi, 330029, China

  • Ningbo Medical Center Lihuili Hospital

    NOT_YET_RECRUITING

    Ningbo, Zhejiang, 315040, China

  • Renmin Hospital of Wuhan University

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430060, China

  • Sichuan Cancer Hospital & Institute

    NOT_YET_RECRUITING

    Chengdu, Sichuan, 610041, China

  • The Affiliated Hospital of Qingdao University

    NOT_YET_RECRUITING

    Qingdao, Shandong, 266000, China

  • The First Affiliated Hospital of Bengbu Medical University

    NOT_YET_RECRUITING

    Bengbu, Anhui, 233030, China

  • The First Affiliated Hospital of China Medical University

    NOT_YET_RECRUITING

    Shenyang, Liaoning, 110001, China

  • The First Affiliated Hospital of Dalian Medical University

    NOT_YET_RECRUITING

    Dalian, Liaoning, 116011, China

  • The First Affiliated Hospital of Fujian Medical University

    NOT_YET_RECRUITING

    Fuzhou, 350005, China

  • The First Affiliated Hospital of Wenzhou Medical University

    NOT_YET_RECRUITING

    Wenzhou, Zhejiang, 325000, China

  • The First Hospital of Jilin University

    NOT_YET_RECRUITING

    Changchun, Jilin, 130033, China

  • The Huashan Hospital Affiliated to Fudan University

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200040, China

  • The Second Affiliated Hospital of Dalian Medical University

    NOT_YET_RECRUITING

    Dalian, Liaoning, 116027, China

  • The first affiliated hospital, college of medicinle, Zhejiang University

    RECRUITING

    Hangzhou, Zhejiang, 310009, China

  • Tianjin Medical University Cancer Institute & Hospital

    NOT_YET_RECRUITING

    Tianjin, Tianjin Municipality, 300060, China

  • Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430030, China

  • Xiangya Hospital of Central South University

    NOT_YET_RECRUITING

    Changsha, 410008, China

  • Zhejiang Cancer Hospital

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, 310009, China

  • the First Affiliated Hospital of Xi'an Jiaotong University

    NOT_YET_RECRUITING

    Xi'an, Shaanxi, 710061, China

  • the second affiliated hospital of Zhejiang University Hangzhou, Zhejiang, China, 310009

    RECRUITING

    Hangzhou, Zhejiang, China

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