Radiation after surgery may keep early oral cancer at bay
NCT ID NCT03853655
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether giving radiation therapy after surgery can prevent early-stage oral cancer from coming back. It included 392 patients with tumors at least 5mm thick. Half received radiation, half were just watched. The main goal was to see if radiation reduced local or regional cancer recurrence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy
What this could lead to
If successful, this could show that adding radiotherapy after surgery lowers the chance of cancer coming back in patients with early oral cancer and thick tumors.
What could go wrong
This trial is completed but results are not yet widely known. The benefit may be small, and radiotherapy has side effects like mouth sores and dry mouth. The study only included certain tumor types and thicknesses, so findings may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Amrita Institute of Medical Sciences
Kochi, Kerala, 682041, India
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Dr. B Barooah Cancer Institute
Guwahati, Assam, 781016, India
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HCG Hospital
Ahmedabad, Gujarat, 380006, India
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Kailash Cancer Hospital and Research Centre
Goraj, Gujarat, 391760, India
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Malabar Cancer Centre
Kannur, Kerala, 670103, India
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Mazumdar Shaw Medical Centre
Bangalore, Karnataka, 560100, India
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Sree Sankara Cancer Hospital
Bangalore, Karnataka, 560004, India
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Tata Memorial Centre
Mumbai, Maharashtra, 400012, India