Radiation after surgery may keep early oral cancer at bay
NCT ID NCT03853655
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether giving radiation therapy after surgery can prevent early-stage oral cancer from coming back. It included 392 patients with tumors at least 5mm thick. Half received radiation, half were just watched. The main goal was to see if radiation reduced local or regional cancer recurrence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiation therapy
- What this could lead to
- If successful, this could show that adding radiotherapy after surgery lowers the chance of cancer coming back in patients with early oral cancer and thick tumors.
- What could go wrong
- This trial is completed but results are not yet widely known. The benefit may be small, and radiotherapy has side effects like mouth sores and dry mouth. The study only included certain tumor types and thicknesses, so findings may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Amrita Institute of Medical Sciences
Kochi, Kerala, 682041, India
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Dr. B Barooah Cancer Institute
Guwahati, Assam, 781016, India
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HCG Hospital
Ahmedabad, Gujarat, 380006, India
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Kailash Cancer Hospital and Research Centre
Goraj, Gujarat, 391760, India
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Malabar Cancer Centre
Kannur, Kerala, 670103, India
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Mazumdar Shaw Medical Centre
Bangalore, Karnataka, 560100, India
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Sree Sankara Cancer Hospital
Bangalore, Karnataka, 560004, India
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Tata Memorial Centre
Mumbai, Maharashtra, 400012, India
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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