Can a simple antibiotic or wound VAC prevent complications after repeat breast surgery?
NCT ID NCT05823467
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at women who have had breast surgery and radiation before and need another breast surgery. Because radiation increases the risk of wound complications, the researchers want to see if giving a week of antibiotics or using a wound VAC (a special dressing) helps prevent these problems compared to no extra treatment. About 105 women will be randomly assigned to one of three groups to find out which approach works best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Trimethoprim/Sulfamethoxazole (antibiotic) and ciNPT dressing (wound VAC)
What this could lead to
If it works, this could show that a simple antibiotic or wound VAC reduces wound complications after repeat breast surgery in women who had radiation.
What could go wrong
This is a small, early-phase trial with only 105 participants, so results may not apply to everyone. Antibiotics can cause side effects like allergic reactions or diarrhea.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Meadowlark Health Centre
RECRUITINGEdmonton, Alberta, T5R 5W9, Canada
Contact Email: •••••@•••••
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St Thomas Surgical Clinic
RECRUITINGSt. Albert, Alberta, T8N 7J6, Canada
Contact Email: •••••@•••••