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Can pomegranate peel extract save Kids' decayed baby teeth?

NCT ID NCT07108738

Symptom relief Sponsor: Tanta University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Oct 06, 2026 · Last updated Oct 07, 2026 · Updated 1 time

Summary

Researchers test whether pomegranate peel extract can serve as a pulpotomy agent for primary molars with deep decay. Thirty children with restorable baby teeth and no signs of severe infection receive the extract after part of the tooth pulp is removed. The trial measures pain, swelling, tenderness, and X-ray changes to see how well the natural material works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pomegranate peel extract applied to the tooth pulp
What this could lead to
If it works, pomegranate peel extract could offer a plant-based option for treating decayed baby teeth and might reduce reliance on synthetic dental materials.
What could go wrong
This is a small, early study in children, so results may not hold up in larger groups or in adults. The extract could fail to control pain or infection as well as standard treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

4 to 7 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Restorable primary molars with deep carious lesions. * Absence of gingival swelling or sinus tract. * Absence of spontaneous pain * Absence of pain on percussion. * Absence of discontinuity of lamina dura * Absence of internal root resorption. * Absence of external root resorption. * Absence of inter-radicular or periapical bone destruction (radiolucency). Exclusion Criteria: * presence of spontaneous pain * presence of gingival swelling or sinus tract * presence of internal or external root resorption * pain on percussion.

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Conditions

The condition(s) this trial relates to.

exposure, dental pulp pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pulp exposure, dental Pulpitis reversible

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Tanta University

    RECRUITING

    Tanta, Egypt

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