Heart failure drug puzzle: study aims to untangle polypharmacy risks

NCT ID NCT07640854

Ongoing Knowledge-focused Sponsor: National Medical Research Center for Therapy and Preventive Medicine Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tracks 130 people with chronic heart failure to understand how taking multiple medications (polypharmacy) affects their safety, adherence, and health outcomes. Researchers will look for patterns of over- or under-prescribing and factors linked to low medication adherence. The goal is to improve prescribing practices and reduce emergency hospital visits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better understand how to prescribe medications safely for heart failure patients taking many drugs, potentially reducing hospital visits and improving quality of life.
What could go wrong: This is an observational registry, not a treatment trial, so it won't directly test a new therapy. The findings may not apply to all heart failure patients, and results depend on accurate reporting from participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

systolic heart failure Treatment Adherence and Compliance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC HEART FAILURE WITH REDUCED AND MILDLY REDUCED EJECTION FRACTION (HFREF AND HFMREF)

Contacts and locations

Locations

National Medical Research Centre for Therapy and Preventive Medicine

Moscow, Russia

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