New vaccine strategy aims to shield lymphoma patients from deadly infections

NCT ID NCT04214444

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a two-step vaccine approach to prevent pneumococcal infections in 26 adults with diffuse large B-cell lymphoma who were receiving chemotherapy with rituximab. The vaccines, Prevenar and Pneumovax, were given in a prime-boost sequence to boost immune protection. The goal was to see if this strategy could improve antibody responses and reduce infection risk in these vulnerable patients.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma lymphoma pneumococcal infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • GYAN

    Tours, 37044, France