Can a simple vaccine boost CAR T-Cell success in lymphoma?

NCT ID NCT04745559

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 27 times

Summary

This study looks at whether giving a pneumococcal (pneumonia) vaccine before and after CAR T-cell therapy helps lymphoma patients build stronger immunity. About 26 adults with certain types of B-cell lymphoma will receive the vaccine at specific times around their CAR T-cell treatment. The goal is to see if this approach improves protection against pneumococcal infections.

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Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.