New shot slashes fat levels in rare genetic disease
NCT ID NCT05902598
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times
Summary
This study tested an injection called Plozasiran in 37 Chinese adults with familial chylomicronemia syndrome (FCS), a rare genetic condition causing extremely high blood fat levels that can lead to severe pancreatitis. The main goal was to see if the drug safely lowers fasting triglycerides (a type of fat) after 10 months of treatment. Participants received either the drug or a placebo, and those who finished the main study could continue on the drug for another year.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Huashan Hospital Affiliated to Fudan University
Shanghai, Shanghai Municipality, China
Conditions
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