New hope for rare fat disorder: safety trial of olezarsen underway
NCT ID NCT05185843
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests the safety of a new drug, olezarsen, in 24 adults with familial chylomicronemia syndrome (FCS), a rare condition causing extremely high blood fats. All participants have previously taken volanesorsen. The study monitors side effects like low platelet counts and kidney function, while also measuring how the drug affects blood fat levels.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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ARC Biosystems, Clinical Assessment Unit (CAU)
Vancouver, British Columbia, V6Z 2C7, Canada
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Centre Hospitalier Universite de Sherbrooke (CHUS)
Sherbrooke, Quebec, J1H 5N4, Canada
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Centre for Heart Lung Innovation
Vancouver, British Columbia, V6Z 1Y6, Canada
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Clinique des Maladies Lipidiques de Quebec Inc.
Québec, Quebec, G1V 4W2, Canada
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Diabetes/Lipid Management & Research Center
Huntington Beach, California, 92648, United States
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Ecogene-21
Chicoutimi, Quebec, G7H 7K9, Canada
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Excel Medical Clinical Trials, LLC
Boca Raton, Florida, 33434, United States
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Karolinska University Hospital Huddinge
Stockholm, 171 77, Sweden
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St. Boniface General Hospital
Winnipeg, Manitoba, R2H 2Ab, Canada
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University of Michigan, Department of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes (MEND)
Ann Arbor, Michigan, 48109-2800, United States
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University of Rochester School of Medicine
Rochester, New York, 14642, United States