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Can threads or plasma smooth out old scars?

NCT ID NCT07775092

Disease control Sponsor: Tanta University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This trial compares two procedures for treating post-traumatic atrophic scars (depressed scars from injury or acne). One group receives a single session of subcision (breaking up scar tissue) plus insertion of poly-L-lactic acid (PLLA) threads, while the other gets subcision combined with platelet-rich plasma (PRP) injections monthly for four months. Researchers will measure clinical improvement, patient satisfaction, side effects, and tissue changes over three months to see which approach works better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Poly-L-lactic acid (PLLA) threads or platelet-rich plasma (PRP), both combined with subcision
What this could lead to
If effective, this could offer a better, longer-lasting option for improving the appearance of post-traumatic atrophic scars.
What could go wrong
This is a small, early-stage comparative study with a short follow-up. Results may not generalize, and both procedures carry risks like infection or scarring.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

Feb 2023

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with post-traumatic atrophic scars. Scar duration of at least 1 year. No treatment received during the previous 6 months. Exclusion Criteria: * Keloids Immunosuppression Coagulative disorders Thrombophilic disorders Any chronic diseases

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Conditions

The condition(s) this trial relates to.

familial pityriasis rubra pilaris

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acne atrophica PRP

Contacts and locations

Locations

  • Tanta University Hospitals

    Tanta, Egypt

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