Massive cancer screening trial tests chest X-Rays for lung cancer

NCT ID NCT01696968

Ongoing Knowledge-focused Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This large study looks at whether regular chest X-rays and health questionnaires can help find lung cancer early and reduce deaths. Over 154,000 people aged 55-74 took part. Researchers compare lung cancer deaths between those who got screened and those who received usual care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show that regular chest X-rays help find lung cancer early and save lives.
What could go wrong: This is an observational screening study, not a treatment trial. It may not prove that screening reduces deaths, and results may not apply to newer screening methods like CT scans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung carcinoma lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CARCINOMA

Contacts and locations

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Locations

National Institutes of Health Clinical Center

Bethesda, Maryland, 20892, United States

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