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New CT scan analysis could spare thousands from unnecessary heart catheterizations

NCT ID NCT01943903

Completed Diagnosis Sponsor: HeartFlow, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a computer analysis of CT scans (called FFRCT) can better guide decisions about heart artery blockages compared to usual care. About 584 people with suspected coronary artery disease took part. The goal was to see if using FFRCT reduces the number of unnecessary invasive angiograms (where a tube is inserted into heart arteries).

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FFRCT (a computer analysis of CT scans to measure blood flow in heart arteries)

What this could lead to

If successful, this could show that FFRCT helps doctors diagnose blocked arteries more accurately, reducing the need for invasive tests.

What could go wrong

This is a completed study, so results are already known. The test may not work as well in all patients or settings, and it adds extra cost and time to standard CT scans.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE

Contacts and locations

Locations

  • Aarhus University Hospital Skejby

    Aarhus, 8200, Denmark

  • CHU Brest - Hopital de Cardiologie

    Brest, 29609, France

  • Cardiovascular Center Aalst

    Aalst, Belgium

  • Cardiovascular Hospital -Interventional Cardiology Dept, Hospices Civils de Lyon and Claude Bernard University France

    Lyon, 69677, France

  • Centro Cardiologico Monzino

    Milan, 20154, Italy

  • Deutsches Herzzentrum München - ISAResearch Centre

    Munich, 80636, Germany

  • Duke University Clinical Research Institution

    Durham, North Carolina, 27705, United States

  • Freeman Hospital - Therapeutics & Cardiac Research Team

    Newcastle upon Tyne, NE7 7DN, United Kingdom

  • Heart Center Leipzig GmbH

    Leipzig, 04289, Germany

  • HeartFlow, Inc

    Redwood City, California, 94063, United States

  • Innsbruck Medical University, Department of Radiology II

    Innsbruck, A-6020, Austria

  • LKH-GRAZ-West - Department of Cardiology

    Graz, A-8020, Austria

  • Stanford University

    Stanford, California, 94305, United States

  • University Hospital Southampton NHS Foundation Trust

    Southampton, SO16 6YD, United Kingdom

  • Universitätsmedizin der Johannes Gutenberg-Universität Mainz

    Mainz, 55131, Germany

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