Can plasma given right away save more burn victims?
NCT ID NCT07212998
First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times
Summary
This study tests whether giving plasma (a part of blood) as soon as possible to adults with severe burns over at least 20% of their body can lower the chance of death or organ failure. About 750 patients will be randomly assigned to receive either early plasma or standard fluids. The goal is to see if early plasma improves recovery compared to usual care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Plasma (blood product)
- What this could lead to
- If it works, this could establish early plasma as a standard treatment to reduce deaths and organ failure after severe burns.
- What could go wrong
- This is an early-stage trial with 750 participants, so results may not apply to all burn patients. Plasma transfusion also carries risks like allergic reactions or infection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
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