Cholesterol drug shows promise in early leukemia trial
NCT ID NCT04512105
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-phase trial tested adding the cholesterol drug pitavastatin to the standard leukemia medicine venetoclax in 6 people with chronic lymphocytic leukemia (CLL) or acute myeloid leukemia (AML). The main goal was to find a safe dose and check for side effects. Researchers also looked at how many patients achieved complete remission.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pitavastatin and venetoclax
What this could lead to
If it works, this could point toward a new combination treatment for certain leukemias.
What could go wrong
This is a very early, small phase 1 trial with only 6 participants. It primarily tests safety and dosing, not effectiveness. The combination may not work or could cause unexpected side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Chao Family Comprehensive Cancer Center, University of California, Irvine
Orange, California, 92868, United States