Misted chemotherapy shows promise for Hard-to-Treat abdominal cancers
NCT ID NCT07271355
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial tests a new method called PIPAC that delivers chemotherapy as a pressurized mist directly into the abdomen during a minimally invasive procedure. It compares this approach plus standard intravenous chemo (FOLFIRI) to standard chemo alone for people with appendix or colorectal cancer that has spread to the lining of the abdomen and cannot be removed by surgery. The study aims to see if the combination helps people live longer. About 129 adults with good performance status will participate.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CTCA at Western Regional Medical Center
Goodyear, Arizona, 85338, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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City of Hope Atlanta Cancer Center
Newnan, Georgia, 30265, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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City of Hope at Chicago
Zion, Illinois, 60099, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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City of Hope at Irvine Lennar
Irvine, California, 92618, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact