New CT scanner could spot hidden stroke risks in neck arteries

NCT ID NCT05764772

Recruiting now Knowledge-focused Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new type of CT scan (photon counting/spectral CT) to see if it can better identify the makeup of plaque in the carotid arteries of people who have had a stroke. Researchers will compare the CT results with MRI scans and, in some cases, with actual plaque tissue removed during surgery. The goal is to see if this advanced CT can reliably tell apart calcium, hemorrhage, and fatty deposits in the plaque, which could help doctors assess stroke risk more accurately.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a more accurate, non-invasive way to identify dangerous plaque in stroke patients, helping guide treatment decisions.
What could go wrong: This is a small, early observational study (70 people) that only tests the imaging method, not a treatment. The new CT may not prove better than existing scans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

carotid stenosis ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CAROTID PLAQUE

Contacts and locations

Locations

University of Pennsylvania Hospital
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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