New light therapy could zap skin cancer without surgery

NCT ID NCT03573401

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 3 trial tests whether a gel called Ameluz® combined with a special red light can effectively treat superficial basal cell carcinoma, a common skin cancer. About 187 adults with at least one lesion are enrolled. The main goal is to see if the treated skin cancer clears up both visually and under a microscope 12 weeks after the last treatment session.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ameluz® (BF-200 ALA) and BF-RhodoLED® lamp

What this could lead to

If successful, this could provide a non-surgical treatment option for superficial basal cell carcinoma, potentially reducing the need for surgery.

What could go wrong

This is a Phase 3 trial, but results are not yet published. The treatment may not be more effective than placebo, and side effects like skin reactions are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

superficial multifocal basal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AboutSkin Research, LLC

    Greenwood Village, Colorado, 80111, United States

  • Alliance Dermatology & Mohs Center

    Phoenix, Arizona, 85032, United States

  • Austin Institute for Clinical Research Inc.

    Houston, Texas, 77056, United States

  • Austin Institute for Clinical Research Inc.

    Pflugerville, Texas, 78660, United States

  • Clinical Research Center of the Carolinas

    Charleston, South Carolina, 29407, United States

  • Cosmetic Laser Dermatology

    San Diego, California, 92121, United States

  • Dartmouth-Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

  • Dermatology Associates PA of the Palm Beaches

    Delray Beach, Florida, 33445, United States

  • First OC Dermatology

    Fountain Valley, California, 92708, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Jordan Valley Dermatology

    West Jordan, Utah, 84088, United States

  • Laser and Skin Surgery Center of Indiana

    Indianapolis, Indiana, 46260, United States

  • Medical Dermatology Specialists

    Phoenix, Arizona, 85006, United States

  • Rochester Dermatologic Surgery

    Victor, New York, 14564, United States

  • Skin Search of Rochester, Inc

    Rochester, New York, 14623, United States

  • The Narrows Institute for Biomedical Research and Education, Inc.

    Brooklyn, New York, 11209, United States

  • University of Florida Dept of Dermatology

    Gainesville, Florida, 32606, United States

  • Virginia Clinical Research, Inc.

    Norfolk, Virginia, 23502, United States