Cure My Disease

Don't miss your cure!

 Log in / Sign up

Sound waves vs. freezing: new skin cancer treatment tested

NCT ID NCT07384078

Disease control Sponsor: Jussi Salonen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether high intensity focused ultrasound (HIFU) works as well as standard cryotherapy (freezing) for treating low-risk basal cell carcinomas and Bowen's disease. About 294 adults with small skin cancers on their body (not face or hands) will be randomly assigned to receive either HIFU or cryotherapy. Researchers will check for cancer recurrence and side effects over 5 years.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
High intensity focused ultrasound (HIFU) device and cryotherapy (liquid nitrogen) procedure
What this could lead to
If HIFU works as well as cryotherapy, it could offer a non-invasive, needle-free option for treating certain skin cancers with potentially less pain or scarring.
What could go wrong
This is an early-stage trial with only 294 participants, so results may not apply to everyone. HIFU might not be as effective as cryotherapy, or could cause unexpected side effects like burns or pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 294 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Dec 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age 18 years or older at the time of informed consent * ability to give informed consent and comply with the treatment protocol and follow-up plan * study lesion located between neck and knees * one of following histologically confirmed diagnosis: Superficial BCC with maximum diameter of 2.0 cm / Nodular BCC with max. diameter of 1.5 cm / BD with max. diameter of 2.0 cm Exclusion Criteria: * Study lesion location in face, head, genitals, hands, or below the knee * Clinical/dermoscopical/histological feature for high-risk/aggressive BCC * Clinical/histological sign for hypertrophic BD * Clinical/dermoscopical/histological feature for Squamous cell carcinoma * Gorlin Golz syndrome * Pregnancy or breastfeeding

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BCC are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

basal cell carcinoma Behcet disease Bowen disease of the skin nodular basal cell carcinoma skin basal cell carcinoma superficial multifocal basal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BCC BD Bowen's disease Nodular basal cell carcinoma Superficial basal cell carcinoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • HUS Iho- ja allergiasairaala

    Helsinki, 00250, Finland

More trials for these conditions

Other studies related to the condition(s) this trial covers.