Sound waves vs. freezing: new skin cancer treatment tested

NCT ID NCT07384078

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether high intensity focused ultrasound (HIFU) works as well as standard cryotherapy (freezing) for treating low-risk basal cell carcinomas and Bowen's disease. About 294 adults with small skin cancers on their body (not face or hands) will be randomly assigned to receive either HIFU or cryotherapy. Researchers will check for cancer recurrence and side effects over 5 years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
High intensity focused ultrasound (HIFU) device and cryotherapy (liquid nitrogen) procedure
What this could lead to
If HIFU works as well as cryotherapy, it could offer a non-invasive, needle-free option for treating certain skin cancers with potentially less pain or scarring.
What could go wrong
This is an early-stage trial with only 294 participants, so results may not apply to everyone. HIFU might not be as effective as cryotherapy, or could cause unexpected side effects like burns or pain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • HUS Iho- ja allergiasairaala

    Helsinki, 00250, Finland

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