No-Needle chemo patch takes aim at skin cancer
NCT ID NCT06608238
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a microneedle patch that delivers the chemotherapy drug doxorubicin directly into nodular basal cell carcinoma, a common skin cancer. 90 adults with small, untreated tumors received either a low-dose, high-dose, or no-drug patch. The goal was to see if the patch could clear the cancer both visually and under a microscope, with the tumor removed at the end for confirmation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- doxorubicin delivered via microneedle patch
- What this could lead to
- If successful, this could offer a needle-free, targeted treatment for common skin cancers, potentially reducing the need for surgery.
- What could go wrong
- This is a small, early-phase study (90 people) and results may not apply to larger or more aggressive tumors. The treatment is not a cure and requires follow-up excision.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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American Skin and Cancer Center - Site#2
Knoxville, Tennessee, 37909, United States
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Arlington Dermatology - Site #1
Rolling Meadows, Illinois, 60008, United States
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Clinical Trials Management, LLC- Site #5
Mandeville, Louisiana, 70448, United States
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HIckory Dermatology Research Center
Hickory, North Carolina, 28602, United States
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Nottingham University Hospitals NHS Trust
Nottingham, East Midlands, NG5 1PB, United Kingdom
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Oak Dermotology - site 07
Naperville, Illinois, 60563, United States
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Paradigm Research -Site #6
San Diego, California, 92108, United States
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Rao Dermatology - Site #3
Highlands, New Jersey, 07716, United States
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Rao Dermotology West Coast -Site #4
Fresno, California, 93720, United States
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Therapeutics Clinical Research -site 08
San Diego, California, 92123, United States
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Virginia Clinical Research Inc - site 11
Norfolk, Virginia, 23502, United States
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