No-Needle chemo patch takes aim at skin cancer

NCT ID NCT06608238

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a microneedle patch that delivers the chemotherapy drug doxorubicin directly into nodular basal cell carcinoma, a common skin cancer. 90 adults with small, untreated tumors received either a low-dose, high-dose, or no-drug patch. The goal was to see if the patch could clear the cancer both visually and under a microscope, with the tumor removed at the end for confirmation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

doxorubicin delivered via microneedle patch

What this could lead to

If successful, this could offer a needle-free, targeted treatment for common skin cancers, potentially reducing the need for surgery.

What could go wrong

This is a small, early-phase study (90 people) and results may not apply to larger or more aggressive tumors. The treatment is not a cure and requires follow-up excision.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NODULAR BASAL CELL CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

basal cell carcinoma nodular basal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • American Skin and Cancer Center - Site#2

    Knoxville, Tennessee, 37909, United States

  • Arlington Dermatology - Site #1

    Rolling Meadows, Illinois, 60008, United States

  • Clinical Trials Management, LLC- Site #5

    Mandeville, Louisiana, 70448, United States

  • HIckory Dermatology Research Center

    Hickory, North Carolina, 28602, United States

  • Nottingham University Hospitals NHS Trust

    Nottingham, East Midlands, NG5 1PB, United Kingdom

  • Oak Dermotology - site 07

    Naperville, Illinois, 60563, United States

  • Paradigm Research -Site #6

    San Diego, California, 92108, United States

  • Rao Dermatology - Site #3

    Highlands, New Jersey, 07716, United States

  • Rao Dermotology West Coast -Site #4

    Fresno, California, 93720, United States

  • Therapeutics Clinical Research -site 08

    San Diego, California, 92123, United States

  • Virginia Clinical Research Inc - site 11

    Norfolk, Virginia, 23502, United States