Can a laser beam replace opioids for knee surgery pain?

NCT ID NCT07750912

Not yet recruiting Symptom relief Sponsor: Mohammad Burney, MD Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This pilot study tests whether photobiomodulation therapy—using a special laser device—can reduce pain in people who go home the same day as their total knee replacement surgery. Participants receive the light therapy as part of their post-operative pain plan, and their pain levels are compared to those of similar patients from the past who did not receive it. The goal is to see if this light-based approach is a feasible and effective way to manage pain after knee surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Photobiomodulation therapy using the LightForce XLi laser device
What this could lead to: If effective, this light-based therapy could become a drug-free addition to pain management after knee replacement, potentially reducing reliance on opioids.
What could go wrong: This is a small pilot study, so results may not apply broadly. The device's use for post-operative pain is off-label, and its benefit over standard care is unproven.

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Conditions

The condition(s) this trial relates to.

agnosia osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOW LEVEL LASER THERAPY PAIN MANAGEMENT POST OPERATIVE ANALGESIA TKA

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