New Pre-Mixed fluid aims to prevent mineral loss during ICU kidney therapy

NCT ID NCT07550894

Not yet recruiting Disease control Sponsor: Sun Yat-sen University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a new pre-mixed fluid that contains phosphate for patients in the ICU who need continuous kidney replacement therapy (CRRT). The standard fluid often washes out phosphate, causing muscle weakness and breathing problems. The trial will compare the new fluid to the standard one in 220 adults across 15 hospitals to see if it keeps phosphate levels normal and is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Phosphate-containing replacement fluid
What this could lead to: If it works, this could provide a safer, more consistent way to maintain healthy phosphate levels during kidney replacement therapy in the ICU.
What could go wrong: This is an early-phase trial with only 220 participants, so results may not apply to all patients. The new fluid could cause electrolyte imbalances or other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute kidney injury infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE KIDNEY INJURY CRITICALLY ILL PATIENTS REQUIRING CONTINUOUS RENAL REPLACEMENT THERAPY SEPSIS

Contacts and locations

Locations

Jiangsu Province Hospital

Nanjing, Jiangsu, China
Nanfang Hospital, Southern Medical University

Guangzhou, Guangdong, China
Renji Hospital, Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, China
Shanxi Provincial People's Hospital

Taiyuan, Shanxi, China
Sichuan Provincial People's Hospital

Chengdu, Sichuan, China
The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China
The First Affiliated Hospital of Henan University of Science & Technology

Luoyang, Henan, China
The First Affiliated Hospital of Xi 'An Jiaotong University

Xi'an, Shaanxi, China
The First Affiliated Hospital of Zhengzhou University

Zhengzhou, Henan, China
The First Affiliated Hospital, Sun Yat-Sen University

Guangzhou, Guangdong, China
The People's Hospital of Guangxi Zhuang Autonomous Region

Nanning, Guangxi, China
The Third Affiliated Hospital, Sun Yat-Sen Unive

Guangzhou, Guangdong, China
Union Hospital Tongji Medical College Huazhong University of Science and Technology

Wuhan, Hubei, China
West China Hospital of Sichuan University

Chengdu, Sichuan, China
Zhujiang Hospital, Southern Medical University

Guangzhou, Guangdong, China

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