New Pre-Mixed fluid aims to prevent mineral loss during ICU kidney therapy

NCT ID NCT07550894

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a new pre-mixed fluid that contains phosphate for patients in the ICU who need continuous kidney replacement therapy (CRRT). The standard fluid often washes out phosphate, causing muscle weakness and breathing problems. The trial will compare the new fluid to the standard one in 220 adults across 15 hospitals to see if it keeps phosphate levels normal and is safe.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Phosphate-containing replacement fluid

What this could lead to

If it works, this could provide a safer, more consistent way to maintain healthy phosphate levels during kidney replacement therapy in the ICU.

What could go wrong

This is an early-phase trial with only 220 participants, so results may not apply to all patients. The new fluid could cause electrolyte imbalances or other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Jiangsu Province Hospital

    Nanjing, Jiangsu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nanfang Hospital, Southern Medical University

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Renji Hospital, Shanghai Jiao Tong University

    Shanghai, Shanghai Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shanxi Provincial People's Hospital

    Taiyuan, Shanxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sichuan Provincial People's Hospital

    Chengdu, Sichuan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Henan University of Science & Technology

    Luoyang, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Xi 'An Jiaotong University

    Xi'an, Shaanxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital, Sun Yat-Sen University

    Guangzhou, Guangdong, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The People's Hospital of Guangxi Zhuang Autonomous Region

    Nanning, Guangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Third Affiliated Hospital, Sun Yat-Sen Unive

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital of Sichuan University

    Chengdu, Sichuan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhujiang Hospital, Southern Medical University

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••