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New hope for advanced prostate cancer: PET-Guided radiation may delay progression

NCT ID NCT06244004

Recruiting now Disease control Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding targeted radiation, guided by a special PET scan, to standard hormone therapy can better control prostate cancer that has spread. About 125 men with metastatic hormone-sensitive prostate cancer will be randomly assigned to receive either standard treatment alone or standard treatment plus radiation to active cancer spots found on the PET scan. The goal is to see if the combination delays cancer progression and improves outcomes.

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Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CASTRATION-SENSITIVE PROSTATE CARCINOMA METASTATIC PROSTATE CARCINOMA STAGE IVB PROSTATE CANCER AJCC V8

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Northwestern Medicine Orland Park

    NOT_YET_RECRUITING

    Orland Park, Illinois, 60462, United States

    Contact Email: •••••@•••••

  • Northwestern Medicine: Delnor

    RECRUITING

    Geneva, Illinois, 60134, United States

    Contact Email: •••••@•••••

  • Northwestern Medicine: Kishwaukee

    RECRUITING

    DeKalb, Illinois, 60115, United States

    Contact Email: •••••@•••••

  • Northwestern Medicine: Warrenville

    RECRUITING

    Warrenville, Illinois, 60555, United States

    Contact Email: •••••@•••••

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Northwestern University Oak Brook IL453

    RECRUITING

    Oak Brook, Illinois, 60523, United States

    Contact Email: •••••@•••••

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