New PET tracer could spot hidden thyroid cancer

NCT ID NCT02856347

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special PET scan tracer called 18F-DOPA can better detect leftover medullary thyroid cancer in lymph nodes after surgery, compared to standard imaging. Twenty-four adults with elevated thyrocalcitonin levels (a sign of residual disease) received the tracer and underwent PET/CT scans. The goal was to see if this method finds more true positive nodes, which could help doctors decide on further treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-DOPA (a radioactive tracer for PET scans)

What this could lead to

If successful, this could improve detection of residual medullary thyroid cancer, guiding more precise follow-up and treatment decisions.

What could go wrong

This is a small, early-stage study (24 participants) focused on imaging accuracy, not treatment. The tracer may not prove better than existing methods, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Carcinoma, Medullary medullary thyroid gland carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Haut-Lévêque

    Bordeaux, France

  • CHU Limoges

    Limoges, France

  • CHU Timone

    Marseille, France

  • ICM Montpellier

    Montpellier, France

  • Institut Claudius Regaud

    Toulouse, 31059, France